What Can You Expect at the Pioneering Oligonucleotide Therapeutics Summit?
The 2nd Oligonucleotide-Based Therapeutics Summit is the dedicated meeting for scientists advancing the next generation of oligonucleotide therapeutics. Across two conference days and a dedicated workshop day, join the researchers tackling the field's most pressing challenges in delivery, chemistry and translation.
Dive into breakthrough approaches spanning blood-brain barrier engineering, AI-designed miniproteins, novel conjugates, circular ASOs and extrahepatic delivery strategies beyond GalNAc and TfR. Through in-depth case studies, new data presentations and candid scientific discussion, gain practical insights to benchmark your programmes, identify emerging opportunities and avoid common translational pitfalls.
Connect with 70+ leaders from across pharma and biotech, including experts in oligonucleotide chemistry, delivery, platform discovery and translational science. Whether you're exploring new disease areas, evaluating delivery platforms or advancing candidates towards the clinic, this summit is designed to help accelerate smarter development decisions.
With exclusive data, interactive discussion and unparalleled access to the people shaping the future of the field, this is where the next chapter of oligonucleotide therapeutics takes shape.
Unmissable Event Highlights: What to Expect
A Brand-New Pre-Conference Workshop Day
For the first time, delegates can go deep on oligonucleotide delivery before the main agenda even begins. Two hands-on workshops, comparing today's leading extrahepatic oligonucleotide delivery strategies, and building the next generation of oligonucleotide conjugates, ligands and linkers, give you a practical framework to take home, not just a seat in the audience.
Live Formats Built for Genuine Debate
Two new interactive formats put the field's most divisive oligonucleotide questions to the test. Watch saRNA, small activating RNA, face direct, moderator-led cross-examination in a live Hot Seat over whether it's a genuine oligonucleotide breakthrough or unproven promise. Bring your own conjugate ligand or linker design challenge to a small-group Innovation Lab to work through it with peers solving the same oligonucleotide delivery problem.
Confronting Endosomal Escape & the Depot Effect Head-On
Three dedicated sessions unpack why tissue accumulation doesn't always mean activity, so you can walk away knowing how to diagnose and design around one of the field's most under-discussed bottlenecks in your own programme, with perspectives from UCSD, UMass Chan Medical School and NanoDe Therapeutics
Beyond the Liver, Beyond CNS
Explore a genuinely disease-agnostic programme spanning oncology, rare disease, metabolic and CNS indications, alongside hard-won industry experience from Vivatides, Evercrisp and Cellado Bio, so you leave with delivery strategies you can apply across your whole pipeline, not just a single indication
An Unfiltered Look Inside Pharma Business Development
A rare, on-the-record conversation with external innovation leaders on exactly what makes an oligonucleotide programme stand out for partnership, in-licensing or acquisition, the closed-door discussion three separate research contacts asked for by name, to know precisely what BD teams are actually looking for before you pitch them
What's New for 2026
Your Preview of the Industry's Biggest Oligonucleotide Discussions
- Pinpoint your must-attend sessions across delivery, conjugates, chemistry, and discovery
- Get a first look at new data before it's shared with the wider industry
- Explore the speaker faculty shaping the future of oligonucleotide therapeutics
- Identify opportunities for your pipeline across key disease areas
- Plan meaningful conversations with the leaders behind the next wave of innovation
Attending Companies Include
Explore the Agenda
Discover innovative oligonucleotide chemistry and delivery breakthroughs across our expert-led sessions, workshops, and panel discussions.
Partner With Us
Position your brand as a leading solution providers and expert at the heart of oligonucleotide drug development.
Join Oligonucleotide Experts
Connect with scientists and decision-makers driving the next generation of ASO and RNA-based therapeutics during dedicated networking sessions.