Assessing & Improving Specificity of Therapeutic siRNAs in Preclinical Models

Time: 4:00 pm
day: Conference Day One

Details:

  • Review how small chemical tweaks can dramatically improve target engagement and hybridization kinetics
  • Unpack the structural features that drive binding specificity and reduce unwanted interactions with non-target transcripts
  • Explore screening methods and predictive tools to de-risk oligo designs before clinical translation

Speakers: