Ganesh Iyer

Company: Opprtna Therapeutics

Job title: Chief Executive Officer

Bio:

Ganesh Iyer is the CEO and Founder of Opprtna Therapeutics, advancing therapeutic aptamers targeting critical proteins in neurodegenerative diseases and oncology. With a Ph.D. in Biochemistry from Rensselaer Polytechnic Institute and over two decades of experience in drug discovery, molecular biology, and biophysics, he has led R&D teams at Alkermes, LifeMine Therapeutics, Warp Drive Bio, and Vertex Pharmaceuticals. Ganesh has advanced multiple targets from discovery to lead optimization, forged strategic academic and CRO collaborations, and developed innovative delivery strategies. His work focuses on translating pioneering research into impactful treatments for CNS disorders and cancer.

Seminars:

Panel Discussion: Overcoming Design Challenges in Next-Generation Oligonucleotides to Maximize Selectivity, Potency & Clinical Impact 9:00 am

What design strategies are most effective in mitigating off-target effects? How do teams prioritize stability vs. delivery vs. potency? What are the emerging trends in oligonucleotide chemistry for next-generation therapeutics?Read more

day: Conference Day Two

Aptamers: Precision Intracellular Modulators Offering Targeted Protein Control Beyond Gene Silencing 10:00 am

Overview of aptamer structure and target binding capabilities inside cells Challenges in chemical stability and strategies to improve molecular retention in vivo Potential for success, sharing success stories in the therapeutic space, rather than just the diagnostic spaceRead more

day: Conference Day Two